News

On June 24-25 2024, the Loda Lab participated in the 35th Pezcoller Symposium held in Trento (Italy). The symposium focused on "Cancer as a Systemic Disease: Interaction between Tumor and Host," a topic of critical importance in contemporary cancer research.

The Pezcoller Symposium, renowned for its contributions to the field of cancer research, is a cornerstone event that brings together leading scientists and researchers from around the world. This year's symposium was chaired by the...

Our postdoctoral associate, Dr. Silvia Daniele Rodrigues, presented her work during a meeting of the New York Prostate Club on June 5, 2024. In her talk, titled "Disrupting ELOVL5 Function Impairs Prostate Cancer Progression in c-Myc-driven Mouse Models", Dr. Rodrigues discussed about her crucial work to understand the interplay between lipogenesis, lipid elongation and prostate cancer progression. To this end, Dr. Rodrigues generated genetically engineered mouse models (GEMM) with deletion...

Androgen deprivation therapy (ADT) is the primary treatment for prostate cancer, but resistance often develops, leading to CRPC. FASN, the main enzyme of de novo lipogenesis, is overexpressed in prostate cancer cells, and drives the synthesis of fatty acids, fueling cancer growth. Our newest publication, “Blocking lipid synthesis induces DNA damage in prostate cancer and increases cell death caused...

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